Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer
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چکیده
منابع مشابه
Nadir PSA level and time to nadir PSA are prognostic factors in patients with metastatic prostate cancer
BACKGROUND Primary androgen deprivation therapy (PADT) is the most effective systemic therapy for patients with metastatic prostate cancer. Nevertheless, once PSA progression develops, the prognosis is serious and mortal. We sought to identify factors that predicted the prognosis in a series of patients with metastatic prostate cancer. METHODS Two-hundred eighty-six metastatic prostate cancer...
متن کاملPSA nadir and outcome in 100 patients with pT3b prostate cancer.
AIM The prostate-specific antigen (PSA) nadir and long-term outcome in patients with pT3b prostate cancer were evaluated. PATIENTS AND METHODS From July 2000 to December 2012, in 100 patients (median age=62 years) with pT3b prostate cancer following radical retropubic prostatectomy (RRP) preoperative and pathological findings predictive of PSA nadir (≤0.2 vs. >0.2 ng/ml) were retrospectively ...
متن کاملThe Utility of Combination of Prostate Specific Antigen (Psa) Nadir Level and Time to Psa Nadir Following Androgen Deprivation Therapy as a Reliable Prognostic Factor in Advanced Prostate Cancer
Androgen deprivation therapy (ADT) is standard systemic therapy for advanced prostate cancer (PCa), however, in some cases temporary remissions may occur and in others cancer can become castration-resistant prostate cancer (CRPC). Most of CRPC still express androgen receptor (AR) and depend on the AR for growth. Several mechanisms that enhance AR signaling in low androgen conditions have been r...
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Introduction: Prostate cancer is one of the most common cancers in Iranian men. PSA(prostate specific antigen) screening is a controversial issue because PSA screening leads to diagnose of patients with low risk prostate cancer who not only do not benefit from treatment but also suffer from complication caused by treatment. On the other hand, without prostate cancer screening, the rate of meta...
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BACKGROUND Patients with early stage prostate cancer have a variety of curative radiotherapy options, including conventionally-fractionated external beam radiotherapy (CF-EBRT) and hypofractionated stereotactic body radiotherapy (SBRT). Although results of CF-EBRT are well known, the use of SBRT for prostate cancer is a more recent development, and long-term follow-up is not yet available. Howe...
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ژورنال
عنوان ژورنال: BMC Urology
سال: 2014
ISSN: 1471-2490
DOI: 10.1186/1471-2490-14-33